| Abstract: The complex tectonic evolution history of the western segment of the Tethyan orogenic belt (zone) has made it one of the world's important Cu, Au polymetallic mineralization belts. Carrying out in-depth research on the mineralization process and summarizing the mineralization laws in this area has significant scientific significance for enhancing the level of regional basic geological research and guiding mineral exploration practices. We systematically collected and comprehensively analyzed regional geological and mineral resource data, with particular focus on elucidating metallogenic characteristics, resource endowment conditions, spatiotemporal distribution patterns of deposits, and their tectonic-magmatic metallogenic contexts. Since the Late Cretaceous, the study area has undergone multiple phases of tectonic-magmatic events, including oceanic and continental subduction, orogeny, back-arc extension, slab rollback and tearing, as well as asthenospheric upwelling. These dynamic mechanisms collectively controlled the regional large-scale Cu-Au mineralization. To date, the area has revealed 39 large to super-large Cu-Au deposits, 31 medium-sized deposits, with numerous small deposits and mineral occurrences widely distributed, demonstrating significant metallogenic potential. The regional deposits exhibit distinct spatiotemporal patterns. Cu-Au mineralization can be classified into seven metallogenic belts: ① Late Cretaceous Apuseni-Banat-Timok-Srednogorie Cu-Au Belt (93–72 Ma), ② Late Cretaceous–Paleocene East Pontides Cu-Au Belt (88–59 Ma), ③ Late Cretaceous East Tauride Cu Belt (81–71 Ma), ④ Eocene Southeastern Anatolian Cu-Au Belt (54–37 Ma), ⑤ Eocene–Pliocene North Macedonia-Rhodope-North Aegean Au-Cu Belt (50–3 Ma), ⑥ Oligocene Tunceli Cu-Au Zone (~26 Ma), ⑦ Miocene Carpathians-Alpine Cu-Au Zone (15–8 Ma). |